benzimidazole derivatives:active class of antioxidants
Benzimidazole Derivatives: Active Class of Antioxidants
Benzimidazole Derivatives: Active Class of Antioxidants Arfa Kamil * 1, Shamim Akhtar . 2, Sarwat Jahan. 1, Aneela Karim. 1, Kiran Rafiq. 3, Sohail Hassan. 2 1. Department of Pharmaceutical Chemistry, Federal Urdu University of Arts Sciences and Technology, Gulshan-e- Iqbal Campus, Karachi. 2
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Benzimidazole Derivatives: Active Class of Antioxidants
Benzimidazole Derivatives: Active Class of Antioxidants. Arfa Kamil * 1, Shamim Akhtar 2, Sarwat Jahan 1, Aneela Karim 1, Kiran Rafiq 3, Sohail Hassan 2. 1 Department of Pharmaceutical Chemistry, Federal Urdu University of Arts Sciences and. Technology, Gulshan-e- Iqbal Campus, Karachi. 2 Department of Pharmaceutical Chemistry, University of ...
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Novel coumarin–benzimidazole derivatives as antioxidants
Coumarin–benzimidazole hybrids were designed, synthesized and evaluated for anti-inflammatory, antioxidant and chronic gastric ulceration potentials. Compounds 4c , 4d and 5a displayed the best anti-inflammatory and antioxidant activities, and proved to be gastric safe.
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List of Research Publications (Last 5 Years)
List of Research Publications (Last 5 Years) Prof. Dr. Shamim Akhtar 1. SarwatJahan, ShamimAkhtar, ArfaKamil, NousheenMushtaq, Z.S. Saify and ... Antimicrobial and antioxidant screening of N′-substituted sulphonyl and benzoyl ... “Benzimidazole Derivatives: Active Class of Antioxidants”.
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Synthesis, antiglycation and antioxidant potentials
Benzimidazole derivatives 1 – 20 were also evaluated for their antioxidant potential. Among the series, compounds 6 (IC 50 = 29.14 ± 0.47 µM) and 10 (IC 50 = 22.42 ± 0.26 µM) showed potent antioxidant activity as compared to standard propyl gallate (IC50 = 29.20 ± 1.25 µM). The greater potential of these compounds i.e.
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Benzimidazoles: A biologically active compounds
The most prominent benzimidazole compound in nature is N-riosyldimethylbenzimidazole, which serves as a axial ligand for cobalt in vitamin B12. The benzimidazole and its derivatives play a very important role as a therapeutic agent e.g. antiulcer and anthelmintic drugs.
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Synthesis and biological evaluation of new Benzimidazole
Group of benzimidazole derivatives are considered as an i mportant class of compounds; they are pr esent in a major of products with br oad sp ectrum in industrial and biological activities.
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Synthesis, Anti-Inflammatory and Anti-oxidant activity
Synthesis, Anti-Inflammatory and Anti-oxidant activity of some substituted Benzimidazole Derivatives. Benzimidazoles are an important class of compounds with a wide spectrum of biological activity ranging from anti-hypertensive, anti-viral, anti-fungal, antitumor and anthelmintic activity. In addition, few N-substituted benzimidazole derivatives have...
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SYNTHESIS AND ANTIOXIDANT ACTIVITY OF THE 2-METHYL
Request | SYNTHESIS AND ANTIOXIDANT ACTIVITY OF THE 2-METHYL BENZIMIDAZOLE | 2-methyl benzimidazole is a heterocyclic organic compound having an important pharmacophoric group which is used in ...
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SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION
ABSTRACT: Benzimidazoles are an important class of compounds with a wide spectrum of biological activity ranging from anti-hypertensive, anti-viral, anti-fungal, antitumor and anthelmintic activity. Benzimidazole rings are the most important nitrogen-containing heterocycles, which are widely explored and utilized by the pharmaceutical industry for drug discovery.
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Benzimidazole Derivatives: Active Class of Antioxidants
Benzimidazoles and its derivatives represent one of the most biologically active class of compounds, possessing a wide spectrum of activities andThere has been growing demand for antioxidants due to report their effective defensive role against oxygen free radical toxicity in our body system.
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Antioxidant activities of indole and benzimidazole derivatives
The synthesized benzimidazole derivatives showed remarkable antioxidant activity in vitro in theIn order to counteract such injurious effects, both the filariids possessed an active antioxidantAn investigation of a number of benzimidazole class preparations, being distinguished by a position of
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Antioxidant and Antifungal Properties of Benzimidazole Derivatives
resistance to azole action because of outer mem-. Antioxidant and Antifungal Properties of. Benzimidazole Derivatives. Canan Kuş. ation of antioxidant and triazole brought a marked. increase in the inhibitory activity of fl uconazole. in susceptible isolates in which the MIC was re
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Benzimidazole Derivative - an overview | ScienceDirect Topics
Benzimidazole derivatives act by interfering with metabolic pathways. Parbendazole has been shown to exhibit a broad-spectrum Anthelmintic activity. This compound is the most potent of a series of substituted 2-amino derivatives, is active against a wide variety of animal nematodes [41].
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Synthesis and antioxidant properties of novel benzimidazole
Some novel benzimidazole derivatives carrying thiosemicarbazide and triazole moieties at the N1 position were synthesized and their in vitro effects on rat liver microsomal NADPH-dependent lipid peroxidation (LP) levels determined by measuring the formation of 2-thiobarbituric acid reactive
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Antioxidant and antifungal properties of benzimidazole derivatives.
Antioxidant and radical scavenging properties of a series of 2-[4-(substituted piperazin-/piperidin-1-ylcarbonyl)phenyl]-1H-benzimidazole derivatives were examined. Free radical scavenging properties of compounds 11-30 and 33 were evaluated for the stable free radical 2,2-diphenyl-1-picrylhydrazyl
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Synthesis, characterization and biological evaluation of benzimidazole
The Benzimidazole derivatives have been the center of the attention of researchers over many years due to high practical value of these compounds 16 - 26.Kamil A, Akhtar S, Jahan S, Karim A, Rafiq K and Hassan S: Benzimidazole Derivatives: Active Class of Antioxidants.
Send InquiryBenzimidazole Derivatives as Antidiabetic Agents
Benzimidazole derivatives; Antidiabetic agents; Pharmacological activity; Mechanism of action; Synthesis. Diabetes mellitus (DM) is a chronic metabolic disease which result due to no production of insulin causing type 1 DM or due to partial and/or insufficient production of insulin causing type 2 DM.
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Supramolecular Assembly of Benzimidazole Derivatives | IntechOpen
Benzimidazole and its derivatives are mostly known by their role in therapeutic drugs and by their pharmacological activities, for example, antimicrobialBenzimidazole derivatives (different “R”) will lead to the synthesis of assemblies of diverse composition and thus morphology and properties.
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Biological Activities of Substituted Benzimidazole Derivatives
new benzimidazole derivatives bearing of benzimidazole derivatives as proton pump inhibitorsHowever and Prostaglandin like activity of combined azacyclic the antioxidant effect shown bya new class of 5HT3 ligands’, Eur J Med Chem investigations of its Heck-type catalytic activity”, J
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